Steven M. Holland, M.D., became the Director of the Division of Intramural Research (DIR) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) in July 2016. As Director, Dr. Holland provides overall executive direction and scientific leadership for the Division’s basic and clinical research activities. Prior to becoming Director, DIR, NIAID, Dr. Holland served NIAID as Chief of the Laboratory of Clinical and Infectious Diseases (LCID). Dr. Holland continues to lead a program in the LCID as chief of its Immunopathogenesis Section.
Dr. Holland’s research areas of special interest have included Job’s syndrome (autosomal dominant STAT3 deficiency) and the genetic conditions predisposing people to mycobacterial infections. More recently, he has been interested in genetic conditions associated with severe coccidioidomycosis and acquired forms of anticytokine autoimmunity predisposing to opportunistic infections. Dr. Holland is the author of more than 500 publications and has been named an NIH Distinguished Investigator. He has received the Infectious Diseases Society of America’s Walter E. Stamm Mentor Award, the American College of Physicians Award for Science, the Boyle Scientific Achievement Award of the Immune Deficiency Foundation, the American Society for Microbiology Abbott Award, the Erwin Neter Award of the Association of Medical Laboratory Immunologists, and the NIH Distinguished Clinical Teacher Award, among other awards. He received his B.A. degree from St. John’s College in Annapolis, Maryland, in 1979 and his M.D. degree from the Johns Hopkins University School of Medicine in 1983. He remained at Johns Hopkins for his internal medicine residency, chief residency, and fellowship in infectious diseases. He came to NIAID in 1989 to study the molecular biology of HIV, and in 1991 moved to the Laboratory of Host Defenses, NIAID, to study phagocytes and phagocyte immunodeficiencies. In 2004, he became chief of LCID, NIAID, a position he held until his appointment as Director, DIR.